1.06576.5000 DI-SODIUM HYDROGEN PHOSPHATE DIHYDRATE MERCK

Description Catalogue Number 106576 Synonyms Sodium monohydrogen phosphate, Sodium phosphate dibasic Description di-Sodium hydrogen phosphate dihydrate Product Information CAS number 10028-24-7 EC number 231-448-7 Grade Ph Eur,BP,USP Hill Formula HNa₂O₄P * 2 H₂O Chemical formula Na₂HPO₄ * 2 H₂O Molar Mass 177.99 g/mol HS Code 2835 22 00 Quality Level MQ500 Physicochemical Information Density 2.1 g/cm3 (20 °C) Melting Point 92.5 °C Elimination of water of crystallisation pH value 9.0 - 9.4 (50 g/l, H₂O, 20 °C) Bulk density 850 - 1000 kg/m3 Solubility 93 g/l Toxicological Information LD 50 oral LD50 Rat > 2000 mg/kg Safety Information according to GHS Storage class 10 - 13 Other liquids and solids WGK WGK 1 slightly hazardous to water Disposal 14 Inorganic salts: Container I. Neutral solutions of the these salts: Container D. Before placing in Container D, check the pH with pH-Universal indicator strips (Item No. 109535). Storage and Shipping Information Storage Store at +2°C to +30°C. Specifications Assay (calculated on dried substance according to Ph Eur) 98.0 - 101.0 % Assay (calculated on dried substance according to USP) 98.0 - 100.5 % Identity passes test Appearance of solution passes test In water insoluble matter ≤ 0.3 % pH-value (5 %; water) 8.9 - 9.2 Chloride (Cl) ≤ 0.005 % Sulfate (SO₄) ≤ 0.02 % As (Arsenic) ≤ 0.0002 % Fe (Iron) ≤ 0.001 % Sodium dihydrogen phosphate (NaH₂PO₄) ≤ 1.7 % Residual solvents (ICH Q3C) excluded by manufacturing process Substances reducing potassium permanganate (as O) passes test Loss on drying (130 °C) 19.5 - 21.0 % Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*). Corresponds to Ph Eur, BP, USP

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